1st place, Conway's Reverse Game of Life 2020
The Process
Our approach was essentially to try as many things as possible and put our processing power on whatever the most promising one was at the time.
A key component was a small web service we built where our scripts could request a random individual to try, and then report their success or failure along with the algorithm name and the time it took to process. We then had a small webpage listing the algorithms and their performance in terms of score improvement per hour. This had several advantages:

we could track how each algorithm did

we could easily plug in new ones without needing to recode timing and performance stats on each separate attempt

it let us distribute the latest changes quickly to whatever available cores we had

It's also helping me write this now as it helps to remember all we tried :). There are 155 rows on the page as I look at it now, and we tried a few more things before we got the service running.
Approaches
To put it in technical terms, we tried "a whole bunch of stuff". What we found is that certain approaches would work really well at the start and then get diminishing returns as they solved the 'easier' versions of the problems, or reached the limit of the approach. Thus we were constantly adding new approaches and rebalancing our power based on their continued performance. These are listed roughly in chronological order.
Simulated Annealing
This is your standard simulated annealing, implemented in C++. It ran superquick and got large improvements at the start. We did it such that each 'run' would try a few thousand epochs on one sample, then report the improvement (if any) and get a new sample to try on.
Genetic Algorithm
We ended up doing three separate implementations of a genetic algorithm. The first one in C++ didn't get many improvements. We were going to abandon the approach but then took heart in seeing Desareca's success and implemented another one in Python. This got rapid improvements early on but started to slow down quickly. As a last optimization we translated the code directly from Python to C++ and got a ~50x pickup on the approach. We kept this one running for a while.
Template Matching
We tried generating all possible 3x3, 4x4, and 5x5 configurations, running them 1, 2, 3, 4, 5 steps, caching the results, and then 'pasting' these in to exact partial matches. It was a bit finicky and didn't work out that well. Our hope was we could paste multiple of these and get a good partial score, but it proved the problem progressed too chaotically to be able to segment it like this. We abandoned it for other approaches.
Z3 Solver
We then learned about the SAT solvers, thanks to James McGuigan's excellent notebook. This was a new tool for us. Here we experimented with trying to find what gives the most improvement: trying the 'easiest' problems first, or the ones that we had the 'most error' on from our other approaches. We quickly discovered that the fewer pixels a stop board had, the easier it was to solve for the solvers, so we prioritized running those first.
Picosat Solver
Some time after the Z3 solver we discovered Picosat, thanks to Serhii Hrynko's notebook. Contrary to what I read on some other reports, we found Picosat to be much faster than Z3.
We tried both approaches of doing an allinone solution (i.e. given stop board find the
board 3 steps back), or trying the iterative, get one step back, then another, etc. We found it was much, much more effective to do the iterative approach. The key was to add additional constraints in order to minimize the number of pixels the solver found on a board. Fewer pixels means more likely to get a father that has its own father, and quicker for the solver to solve. We implemented a search algorithm that would use binary search to find the number of dead cell constraints to add, and then it would get a random subset of these and yield solutions. If the solutions failed it'd loosen the constraint (requiring fewer dead pixels) and if the search failed with no constraints we
backtracked one level up.
Very effective was imposing a timeout on the solver. At first we gave them a 1 minute timeout and solved all we could within a minute. Then we expanded to 10 minutes, then an hour, and finally by the end we were running them with a 2hour timeout before aborting. The effect of the timeout was to essentially restart the search a different firststepback board. From observation we found the solver would get stuck down a hopeless branch, either one that has no eventual solution, or one where it might but it's so computationally intensive to try each step that it would take forever to run.
Partial Solvers
The more the solvers ran, the greater diminishing returns we found. We experimented a lot and eventually found something that would help, namely to zeroout the edges of the stop board and have the solvers partially solve this. This would generate a start board that gets the center of the solution fully correct, and then our iterative approaches would pick them up and gradually improve them.
The inspiration from this came from seeing that as the boards evolve, the solvers are very quick up until the wrappedaround edges 'touch' each other, then it becomes very difficult to find a solution. The hardest cases at the end were the ones that looked sort of like a cosmic background radiation where everything was very dense and uniform. It's interesting that there were 5 delta2 problems and 129 delta3 problems that eluded solving until the very end.
Incremental Exhaustive Search
At this point we joined forces with the formidable Vlad Golubev, which gave us a huge boost to our score right away. I will link to his writeup once it's available, but to summarize here he implemented a crazyfast C++ exhaustive search algorithm. The approach was to flip each pixel, pick the best board and then continue until there's a board with no singlepixel improvement. Then he would flip a random 5 pixels and restart from there. The huge speedup he found was by, whenever he flipped a pixel, only recalculating the affected neighbors.
Kissat
As the competition got stiff at the very end we scrambled to find another magical pickup. If picosat was so much faster than Z3, maybe another SAT solver would be even faster?
We tried cryptosat, microsat, and kissat. Interestingly there was no one solver that performed the best on all problems. Cryptosat was generally slower although on some small sets would give a ~10% pickup. Microsat was faster than picosat on small instances, but slowed down on harder problems. Kissat was much slower on small instances than picosat. We were about to give up but then we saw Kissat solve a problem in 5 seconds that took picosat 60 seconds to solve. There was hope yet!
We plugged kissat instead of picosat and let it run and we started getting huge gains again. By this point we had only the harder of the problems left to solve so kissat was a clear gain on all of these. Here I want to personally thank the SAT solver community for having everyone take input in DIMACS form, it made it easy to plugandplay different solvers :) .
Final Optimizations
As the clock ticked down we tried changing the order of the problems again. We managed to solve the remaining delta2s, then distributed some cores on delta3, some on delta4, and others to pick random from what was left.
Conclusion
As future work, it would be interesting if we could get to 0. The largest optimization I could think is to improve the search on the solvers, particularly when to backtrack. As the larger problems take so long to solve it made it hard to tweak this, especially near the end where every restart could lose us up to 2 hours of progress on each problem. The other thought was to add constraints to "decluster" solutions, e.g. to not have a thick cluster of 2x3 pixels or a 5pixellong row or line. We experimented with this but didn't have time to get anything conclusive at the end.